- Estrogen is known as the “female hormone”. As females have small amounts of testosterone, in turn males have small amounts of estrogen. Increased estrogen can lead to things like increased body fat, water retention, and gymnecomatia.
- ALPHA Anti-Estrogen ([(S)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4- methoxyphenyl)-4-H-1-benzopy-ran-4-one]) is a citrus bio-flavonoid and a potent anti-aromatase. Aromatase is an enzyme involved in the process that occurs when certain hormones convert to estrogen. When testosterone is increased, estrogen also increases as the body fights to stay in homeostasis (balance). ALPHA Anti-Estrogen reduces the formation of estrogen in the body.
For more information on each of the ingredients in the ALPHA formula, please click on the links below:
ALPHA Test | ALPHA Anti-Estrogen | ALPHA GH
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Research supporting ALPHA Anti-estrogen (3', 5, 7-Trihydroxy-4'-Methoxyflavone):
- Juniewicz, P.E., et al., "Aromatase Inhibition in the Dog. Effect on Serum LH, Serum Testosterone Concentrations and Spermatogenesis," Journal Urology 139.4 (1988) : 827-31.
- Cho J. Antioxidant and neuroprotective effects of hesperidin and its aglycone hesperetin. Arch Pharm Res. 2006 Aug;29(8):699-706.
- J. Lampe and J. Chang, Interindividual Differences in Phytochemical Metabolism and Disposition, Semin Cancer Biol. 2007 October; 17(5): 347–353.
- Murphy LC, Dotzlaw H, Leygue E, Douglas D, Coutts A, Watson PH. Estrogen receptor variants and mutations. J Steroid Biochem Mol Biol. 1997;62(5–6):363–372.
- Kellis, J.T., Jr., and Vickery, L.E. (1984). Inhibition of human estrogen synthetase (aromatase) by flavones. Science 225, 1032-1034
- Pelissero, C., Lenczowski, M.J., Chinzi, D., Davail-Cuisset, B., Sumpter, J.P., and Fostier, A. (1996). Effects of flavonoids on aromatase activity, an in vitro study. J. Steroid Biochem. Mol. Biol. 57, 215-223.
- Sanderson, J.T., Hordijk, J., Denison, M.S., Springsteel, M.F., Nantz, M.H., and van den Ber, M. (2004). Induction and inhibition of aromatase (CYP10) activity by natural and synthetic flavonoids compounds in H295R human adrenocortical carcinoma cells. Toxicol. Sci. 82, 70-79.
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